Dr Seema Alam

Dr Seema Alam

Professor

Experience

Dr Seema Alam has joined ILBS in December 2010 as additional professor Pediatric Hepatology. Her fellowship at Kings College's Pediatric Liver unit came handy in developing the first ever department of Pediatric Hepatology in the country. The department has grown to the present strength since then and the pediatric liver transplantation program was also initiated in September 2011. ILBS has performed about 12 pediatric Living and one Deceased Donor Liver Transplantation in about 14 months. The OPD attendance and indoor occupancy has grown many folds in the last 2 years of her stay here. Her keen interest in metabolic liver disease is opening new arena of diagnosis which is exclusive to this department. The department has been working in the right direction is evident from the fact that this year it has bagged two of the four awards in the hepatology section of the Pediatric gastroenterology subchapter for original work. This year the department starts the PDCC course in Pediatric hepatology.

Number of publications

62

Publications

Total number of publications (till date)

  • Clinical and Prothrombotic Profile of Hepatic Vein Outflow Tract Obstruction. Accepted manuscript in Indian J Pediatrics.
  • Non-cirrhotic portal hypertension. Accepted manuscript in Journal of Hepatology.
  • Clinicopathological Conference - Neonatal cholestasis with ductal paucity and steatosis. Indian Pediatrics March 2013;50(16):316-320.
  • Phenotypic Variation and Long-term Outcome of Children with Congenital Hepatic Fibrosis.
  • The Water Halo Sign with Calcium. J Pediatr 2013 Apr 25. doi:pii: S0022-3476(13)00320-X. 10.1016/j.jpeds.2013.03.044. [Epub ahead of print].
  • Congenital Extrahepatic Portocaval Shunt with Trisomy 8 and Ductal Paucity. Under peer review in J Pediatr Gastroenterol Nutr.
  • The efficacy of zinc supplementation in young children with acute lower respiratory infections: a randomized double-blind controlled trial. Clin Nutr. 2013 Apr;32(2):193-9. doi: 10.1016/j.clnu.2012.08.018. Epub 2012 Aug 31.
  • IgA anti-tTG antibodies in children with severe short stature without gastrointestinal manifestations. Indian J Gastroenterol. 2012 Jan;31(1):32-3. doi: 10.1007/s12664-011-0160-2. Epub 2012 Feb 4.
  • Novel nonsense mutation of ABHD5 in Dorfman Chanarin syndrome with unusual findings: A challenge for genotype phenotype correlation. European Journal of Medical Genetics 2012; 55:173-177.
  • Hepatocellular carcinoma in an adolescent with Celiac disease. J Pediatr Gastroenterol Nutr 2012 Jul 9
  • Anomalous Pancreaticobiliary Junction (APBJ). J Pediatr Gastroenterol Nutr. 2012 Apr 24.
  • Efficacy and Safety of Saccharomyces boulardii in Acute Childhood Diarrhea: A Double Blind Randomised Controlled Trial. The Indian Journal of Pediatrics (2011): 1-5, October 14, 2011.
  • Determinants of vitamin A deficiency amongst children in Aligarh district, Uttar Pradesh. Indian Pediatr. 2011;48:861-661.
  • Long-term follow-up of children with 6-thioguanine-related chronic hepatoxicity following treatment for acute lymphoblastic leukaemia. J Pediatr Gastroenterol Nutr. 2011 Nov;53(5):478-9. 
  • Potentially Modifiable Micro-Environmental and Co-Morbid Factors Associated with Severe Wasting and Stunting in Children below 3 Years of Age in Aligarh District. Indian J Community Med. 2010 Apr;35(2):353-5. 
  • Global developmental delay and its determinants among urban infants and toddlers: a cross sectional study. Indian J Pediatr. 2010 Sep;77(9):975-80.
  • Screening children with severe short stature for celiac disease using tissue transglutaminase. Indian J Pediatr. 2010 Apr;77(4):387-90.
  • Management of acute diarrhea: from evidence to policy. Indian Pediatr. 2010 Mar;47(3):215-7.
  • Rational drug Therapy, chapter in the Book 'Acute Diarrhea' edited by A K Patwari." Publisher Elsevier.
  • "Inborn errors of Metabolism" chapter in the textbook of Biotechnology.
  • Delivered a lecture on"Etiology of chronic liver disease: Indian Perspective" at PEDGASTROCON 2012, 22nd National Conference of Pediatric Gastroenterology, Hepatology and Nutrition held at SGPGI, Lucknow on November 2-4, 2012.
  • Delivered a lecture on "Pediatric acute liver failure" at TRANCRIT 2012 - Symposium on "Acute Liver Failure: From Critical Care to Liver Transplantation" at ILBS April 22, 2012.
  • Delivered a lecture on "Investigative work up of neonatal cholestasis" at PEDICON workshop in January 2012
  • Chairperson for a session on Neonatal Cholestasis. Liver Histopathology conference at GB Pant Hospital, on January 20-21, 2012.
  • Delivered a lecture on "Metabolic liver disease in Pediatric acute liver failure" at APASL school of Hepatology, at ILBS Jan 15, 2012.
  • Delivered a lecture on "Antibiotic associated diarrhea" - Update on Management of acute diarrhea at PGIMER Chandigarh, Oct 2012
  • Delivered a lecture on "Acute Liver failure and metabolic liver disease" at IAP KOTA on July 29, 2012
  • Poster presentation on "Hepatocellular carcinoma in an adolescent with celiac disease" at International Symposium on HCC titled "Management paradigms for Hepatocellular Carcinoma: Current and Future." at New Delhi on April 7-8, 2012.
  • Oral presentation on "Transient elastography accurately predicts fibrosis & complications of portal hypertension in children" at PEDGASTROCON-2012, 22nd National Conference of Pediatric Gastroenterology, Hepatology and Nutrition at SGPGI, Lucknow on November 2-4, 2012.
  • Oral presentation on "Low uric acid is an important biochemical clue for the diagnosis of Wilson disease" at PEDGASTROCON-2012, 22nd National Conference of Pediatric Gastroenterology, Hepatology and Nutrition held at SGPGI, Lucknow on November 2-4, 2012. Paper won first prize in Liver section in oral papers category.
  • Poster presentation on "Congenital portocaval shunt - Abernethy type 1 b malformation with ductal paucity, cholestasis, hepatopulmonary syndrome and developmental delay" at PEDGASTROCON-2012, 22nd National Conference of Pediatric Gastroenterology, Hepatology and Nutrition held at SGPGI, Lucknow on November 2-4, 2012.
  • Poster presentation at "Protocol based diagnosis and management of Metabolic liver disease" at ISGCON 2012, Annual Conference of Indian Society of Gastroenterology, at Jaipur from November 29-December 2, 2012. Won the best poster award.
  • Delivered a lecture on “Drug Induced Liver Injury” at the Kunwar Viren Oswal Postgraduate Course in Pediatric gastroenterology & Hepatology.  Apollo Hospital, Delhi on 28 Aug-1st Sep, 2013.
  • Delivered a lecture on “Role of anti-oxidants in children with NAFLD” at NAMS PGI symposium on Non-alcoholic fatty liver disease in children and adolescents at PGIMER, Chandigarh on 10th March, 2013.
  • Delivered a lecture on “Approach to Metabolic Liver disease in children” at PEDICON 2013 at Kolkata on 7-10th January, 2013. 
  • Presented an oral paper at International Congress of Inborn Errors of Metabolism (ICIEM) 2013 at Barcelona on 2-6th September, 2013. Alam S, Khanna R, Rawat D, Sood V. “Protocol based Approach in Metabolic Liver disease in a developing country” 
  • Presented a poster at International Congress of Inborn Errors of Metabolism (ICIEM) 2013 at Barcelona on 2-6th September, 2013.  Alam S, Khanna R, Sood V, Rawat D. “Prediction of poor outcome on medical therapy in Wilson’s disease presenting as chronic liver disease: Is the New Wilson Index helpful?” 
  • Presented a poster at International Congress of Inborn Errors of Metabolism (ICIEM) 2013 at Barcelona on 2-6th September, 2013. Alam S, Khanna R, Sood V, Rawat D
  • Moderator for a case discussion on “Splenohepatomegaly in a child” at Pediatric Liver Foundation Meet at Mumbai on 14-15th December, 2013.  
  • Moderator for a case discussion on “Hepatomegaly in a child” at Children’s Liver Disease  Foundation Meet at Mumbai on 14-15th December, 2013.  
  • Moderator for a case discussion on “Cholestatic liver disease in a 3-year old child” at Pediatric Liver Foundation Meet at Mumbai on 14-15th December, 2013.  
  • Panelist for a case discussion on “Neonatal Liver failure” at Pediatric Liver Foundation Meet at Mumbai on 14-15th December, 2013.  
  • Panelist for a case discussion on “Rickets and Liver disease” at Pediatric Liver Foundation Meet at Mumbai on 14-15th December, 2013.